Chemical Studies on “Bukuryo”, Sclerotia of Pachyma Hoelen RUMPH. (VI)

Studies on Digitalis VI

T IS undisputed that the administration of digitalis to patients with many forms of congestive heart failure results in an improvement in both the clinical state and in the abnormal circulatory dynamics that are characteristic of heart failure.'-6 The effects of digitalis in subjects without heart failure are less well defined. Although some glycosides augment the contractile force of nonfailin...

Chemical Studies on Bacterial Agglutination Vi. the Agglutinin Content of ~tisera to Hemolytic Streptococci

In most of the bacterial agglutinating systems previously studied by the quantitative method (1-5) well defined capsular polysaccharide antigens and their corresponding antibodies were principally involved. The greater part of the antibody produced as a result of intravenous injections of microorganisms such as type-specific pneumococci or It. influenzae reacts with these capsular antigens, rel...

OPTICAL STUDIES OF COLORED CHEMICAL SPECIES

Evanescent wave spectroscopy using thin optically transparent electrodes and multiple reflections allows unique observations of the electrochemical interphase since the region of solution sampled is typically 100 nm from the electrode in the visible spectral region. This technique is found to be highly sensitive to the presence of absorbing adsorbed species

Chemical biology studies on norrisolide.

The cellular activity of norrisolide (7), a novel Golgi-vesiculating agent, was dissected as function of its chemical structure. This natural product induces irreversible vesiculation of the Golgi membranes and blocks protein transport at the level of the Golgi. The Golgi localization and fragmentation effects of 7 depend on the presence of the perhydroindane core, while the irreversibility of ...

Chemical Studies on Sludge Digestion